Although patients with evidence of pulmonary toxicity had more severe baseline left ventricular dysfunction as judged by radionuclide ejection fraction (0
They were required to have dyspnea on exertion or paroxysmal nocturnal dyspnea, a left ventricular EF of ≤40% as measured with radionuclide
We present a case of ALF secondary to drug-induced liver injury (DILI) from amiodarone use
We have received reports of an abnormal slowing of the heart rate (bradycardia) when amiodarone is taken together with either the hepatitis C drug Harvoni
Signs and symptoms of left ventricular diastolic dysfunction
Amiodarone, an iodinated benzofuran derivative with Class I, II, III, and IV antiarrhythmic properties, is the most commonly used antiarrhythmic drug used to treat supraventricular and ventricular arrhythmias
HARVONI treatment may result in slowing of the heart rate along with other symptoms when taken with amiodarone (Cordarone ®, Nexterone ®, Pacerone ®), a medicine used to treat certain heart problems
3% for general cardiac dysfunction
Amiodarone is a benzofuran compound ( Figure 1) that contains approximately 37% iodine by weight and bears a remarkable structural resemblance to thyroid hormones ( Figure 1 (a) — (c)) [ Rao et al
1,2 Amiodarone exerts negligible negative inotropic activity and causes a low rate of ventricular proarrhythmia, rendering this
Half-Life Elimination
Amiodarone is an antiarrhythmic drug, containing 37% iodine by weight, and with structural similarities to thyroid hormones
Left ventricular failure occurs when there is dysfunction of the left ventricle causing insufficient delivery of blood to vital body organs
Amiodarone was developed originally as an antianginal agent in Belgium (Labaz Inc
Because of adverse drug reactions, proper use is essential to
(1) No amiodarone use before or after LVAD
Toxicity is related to cumulative dose and typically occurs after at least