Amitriptyline should not be used with phenylephrine except in cases of emergency
The main types are: Drug-drug interaction
Phenylephrine—Studies on birth defects have not been done in either humans or animals with phenylephrine
Amitriptyline increases the effects of Phenylephrine
Applies to: amitriptyline and C Phen (chlorpheniramine / phenylephrine) Amitriptyline should not be used with phenylephrine except in cases of emergency
It’s generally considered safe to take antidepressants while taking cold medicine
You shouldn't take cold and flu remedies that contain a decongestant such as pseudoephedrine or phenylephrine while you're taking amitriptyline
Cyclobenzaprine (Amrix) is a muscle relaxant that’s FDA approved to treat muscle spasms from muscle or bone problems
If your doctor wants you to take this combination a dosage adjustment may be necessary
Applies to: amitriptyline and Theraflu Flu & Sore Throat (acetaminophen / pheniramine / phenylephrine) Using amitriptyline together with pheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal
Both Amitriptyline and Baclofen can cause sedation, which might affect the ability to perform skilled tasks (see 'Drugs and Driving' in Guidance on Prescribing )
Do not drive Applies to: amitriptyline and Mucinex Children's Night Time Multi-Symptom Cold (acetaminophen / diphenhydramine / phenylephrine) Using amitriptyline together with diphenhydrAMINE may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating
In this video, learn about common medications that interact with melatonin supplements, such as by causing excessive drowsiness or
This includes many antidepressants, sedatives, and anticholinergic medications like diphenhydramine (Benadryl)
bone marrow suppression
When taken together, TCAs and clonidine can make you too drowsy
This includes nosebleeds, unexplained bruising, and bleeding in your urine or gums
Using amitriptyline together with isoproterenol can affect the rhythm of your heart
Using amitriptyline together with pheniramine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased
Using amitriptyline together with dextromethorphan can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred