8 g/mol
1
There are 28 non-H bond (s), 23 multiple bond (s), 4 rotatable bond (s), 23 aromatic bond (s), 1 five-membered ring (s), 3 six-membered ring (s), and 1 Imidazole (s)
It has 4 aromatic rings attached to an atom in the form of tetrahedral carbon (sp3-hybridised) that is very steric in this atom
It discusses the names, formula, molecular weight, and structure, drug properties, and appearance, color, odor, and taste of clotrimazole
It contains four aromatic rings bonded to a tetrahedral (sp3 hybridized) carbon atom, causing a highly steric encumbrance on this atom
Source publication Design and Synthesis of 2-Methyl and 2-Methyl-4-Nitro Imidazole Derivatives as Antifungal Agents Article Full-text available Jan 2009 These PXRD data are compatible with the structure of clotrimazole presented in the Cambridge Structural Database (CSD ref
It discusses the names, formula, molecular weight, and structure, drug properties, and appearance, color, odor, and taste of clotrimazole
Comment: Clotrimazole is an anti-fungal agent
This medicine may also be used for other problems as determined by your doctor
an unpleasant sensation in the mouth
At last,Clotrimazole(23593-75-1) safety, risk, hazard and MSDS Betamethasone Dipropionate and Clotrimazole | C50H54ClFN2O7 | CID 174856 - structure, chemical names, physical and chemical properties, classification, patents Clotrimazole is a derivative of imidazole and has similar antimicrobial action and activity to ketoconazole
a, a -diphenylbenzyl)imidazole [ 23593-75-1 ]
In the presence of the endogenous TRPM3 ligand, pregnenolone sulfate (PS), the antifungal compound clotrimazole (Clt) augments Ca 2+ signaling and opens a non-canonical pore, permeable to Na +, which aggravates TRPM3-induced pain
clotrimazole supports these calculated models of the structure of clotrimazole
This drug is an azole antifungal, in the same drug family as [ketoconazole] and [itraconazole]
Clotrimazole cream USP, 1% contains clotrimazole, a synthetic antifungal agent having the chemical name {1- (o-Chloro-α, α-diphenylbenzyl)imidazole}; the molecular formula C 22 H 17 ClN 2; a molecular weight of 344
Binding studies indicate that clotrimazole exhibits tight binding to CYP3A5 with Clotrimazole 2, on the other hand, is an imidazole derivative with antifungal activity that is only indicated for topical use due to its toxicity (Figure 1)
1 - 0
Protons studied by 1 H-NMR are symbolised as follows, according to the carbon to which they are linked: atom 4, A; atom 12, B; atom 5, C Clotrimazole is a member of the azole class of synthetic antimycotic agents that were discovered in the 1960s
[11,30] The retention time of Clotrimazole, Imidazole and 2-chlorophenyl phenyl methanone (2-chlorobenzophenone)was 8
It interferes with the production of new sterols that normally give a fungal cell its structure
The structure of complexes t hat may be generated by h ydrogen Description: Mechanism of Action: Clotrimazole is an imidazole antifungal that exerts its antimicrobial activity by binding to phospholipids in the cell membrane and altering cell wall permeability, thereby causing a loss in essential intracellular elements
Here we describe the optimization of this class of Superficial sites of infection in vaginal and vulval candidiasis (dose for 1% or 2% cream) for clotrimazole By vagina using cream
Slow dissolution in the mouth results in the binding Clotrimazole-d5 | C22H17ClN2 | CID 45038700 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities Clotrimazole, bis-phenyl- (2-chlorophenyl)-1-imidazolyl methane, is a uniquely antifungal compound
It is in the imidazole class of drugs
An overview of the use of azole agents for the treatment of various systemic fungal infections will be reviewed here
SAR stu
Figure 12: Reference chromatogram of Clotrimazole Clotrimazole is an imidazole antifungal agent with relatively low toxicity
It inhibits biosynthesis of the sterol ergostol, an important component of fungal CELL MEMBRANES
67 D, and is highly soluble in water
, 2013 Novel crystalline adducts of clotrimazole with pharmaceutically acceptable coformers were prepared
Clotrimazole is an imidazole derivative, an antifungal compound and is a CYP (cytochrome P450) inhibitor
This chapter provides an overview of clotrimazole
Chemical structure of clotrimazole
Clotrimazole lozenges are dissolved slowly in the mouth to prevent and
0percent of C 22 H 17 ClN 2 ,calculated on the dried basis
Other names: 1H-Imidazole, 1-[(2-chlorophenyl) These computed models of clotrimazole's structure are
5 to 1 mg/cm Clotrimazole is a member of the azole class of synthetic antimycotic agents that were discovered in the 1960s
from publication: Design and Synthesis of 2-Methyl and 2-Methyl-4-Nitro Imidazole Derivatives as Antifungal Agents | Two series (a and b) of N-substituted A comparison between fluconazole tablets and clotrimazole troches for the treatment of thrush in HIV infection
[8] Navas and co-workers
For the treatment of oral candidiasis, clotrimazole is available as a 10-mg troche (see Table 34-2)
Clotrimazole is a member of the azole class of synthetic antimycotic agents that were discovered in the 1960s
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Clotrimazole formally also is an imidazole derivative because of the presence of an imi dazole ring in its structure
Clotrimazole side effects
Clotrimazole has antibacterial activity
Call your doctor for medical advice about side effects
Clotrimazole 2, on the other hand, is an imidazole derivative with antifungal activity that is only indicated for topical use due to its toxicity (Figure 1)
Chemsrc provides Clotrimazole(CAS#:1448670-11-8) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc