Ordinarily, optimal clinical response is achieved at daily doses below 60 mg/kg/day
Depakote ( divalproex delayed-release [DR]) and Depakote ER (divalproex extended-release) are brand-name prescription medications
Divalproex sodium oral tablet (Depakote, Depakote ER) is used to treat seizures, treat bipolar disorder, and prevent migraine
Medically reviewed by Sophia Entringer, PharmD
DEPAKOTE® (divalproex sodium) delayed-release tablets, DEPAKOTE® ER (divalproex sodium) extended-release tablets, and DEPAKOTE® Sprinkle Capsules (divalproex
Depakote ER is a valproate and is indicated for the treatment of acute manic or mixed episodes associated with bipolar disorder, with or without psychotic features
Purpose: A novel once-daily divalproex-extended release (ER) dose formulation has been developed; this formulation prolongs the therapeutic serum levels of the drug, compared with the twice-daily conventional divalproex-delayed release (DR) formulation
This medicine is an anticonvulsant that works in the brain tissue to stop seizures
When treating migraine: Not for use in pregnancy
Call your doctor right away if you have signs of liver problems like dark urine, feeling tired, not hungry, upset stomach or stomach pain, light-colored stools, throwing up, or yellow Efficacy of extended-release tablets (e
33 subjects discontinued; the most common reasons for discontinuation were adverse events, withdrawal of consent and lost to Divalproex sodium oral tablet (Depakote, Depakote ER) is used to treat seizures, treat bipolar disorder, and prevent migraine
Two of the pediatric studies were double-blinded placebo-controlled trials to evaluate the efficacy of Depakote ER for the indications of mania (150 patients aged 10 to 17 years, 76 of whom were on Depakote ER) and migraine (304 patients aged 12 to 17 years, 231 of whom were on Depakote ER)
Controlled substances include opioids, stimulants, depressants
The name or appearance may be different in various countries but usually the dose (measured in milligrams, abbreviated "mg") will be the same
Divalproex sodium is used to treat certain types of seizures (epilepsy)
Patients should be monitored for the emergence or worsening of depression, suicidal thoughts or behavior, and/or any unusual mood or behavior changes
Valproic acid has an average rating of 5
Depakene; Depakote; Depakote DR; Depakote ER; Depakote Sprinkles; Stavzor; Canadian Brand Name
in addition to their original antiepilepsy drug (AED), either Depakote or placebo
It works by calming overactive nerves in your body
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The newest formulation of divalproex is in the form of an extended-release tablet, Depakote ER ® (ER), which provides a once-daily administration option for the treatment of acute manic or mixed episodes of bipolar disorder, independent of the presence of psychotic features ( Abbott Laboratories 2006 )