Recommended starting dosage ranges are given as micrograms per kilogram of body weight (mcg/kg) and are taken once per day
Adjust the dose by 12
The objective of this review is to provide an overview of (1) when administration of levothyroxine is necessary, (2) initial dosing and subsequent
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For oral dosage form (capsules): Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by
Usual initial dose: 12
For the treatment of hypothyroidism (oral): Adults who are healthy and diagnosed with hypothyroidism for a few months should receive an initial dose of 1
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For adults aged 50 years and over, with cardiovascular disease, or severe hypothyroidism — initially 25 micrograms once daily; adjusted in steps of 25 micrograms every 4 weeks
Therapy consists of thyroid hormone replacement, unless the hypothyroidism is transient (as after painless thyroiditis or subacute thyroiditis) or reversible (due to a drug that can be discontinued)
By 12
Dose: individualize dose PO qd; Start: 10-15 mcg/kg/dose PO qd, then adjust dose q2wk; Info: adjust dose based on TFTs; use lower start dose and incr
5 to 25 mcg increments every 4 to 6 weeks until clinically euthyroid and TSH normalized
Your doctor may adjust your dose as needed or
An inadequate response to daily doses ≥ 300 mcg/day is rare and may
3 mcg/kg of LBM that could be generally applied to all ranges of BMIs, especially in hypothyroid obese patients
6 micrograms per kilogram of body weight per day (rounded to the nearest 25 micrograms) If symptoms do not improve after starting levothyroxine, re-measure TSH and if the level remains raised, adjust the dose
As levothyroxine is usually administered over a patient's lifetime, physiological changes throughout life will affect the dose of levothyroxine required to maintain euthyroidism
Liquid dose = 2 mg/ (1 mg / 2 mL) = 4 mL
5-25 mcg q4-6weeks until patient becomes euthyroid and serum TSH concentration normalized; adjustments q6-8weeks also used; Dose range: 100-125 mcg PO qDay; Severe
There are simple formulas based only on body weight or body mass index, and there are also more Available tablet strengths and precision of LT4 dosing
1,2 Postoperatively, many patients take Levothyroxine (LT4), a synthetic form of thyroxine, as a lifelong
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Levothyroxine (LT4) is the most widely prescribed drug in the United States