Disulfiram mechanism of toxicity

In the blood, it changes to diethyldithiocarbamic acid (DDC), which is degraded to form diethylamine and carbon disulfide. It binds irreversibly to aldehyde dehydrogenase, leading to accumulation of toxic acetaldehyde after ethanol ingestion

2024-03-29
    Levothyroxine and heart disease
  1. Generic Name
  2. •dark urine
  3. Mechanism of action
  4. It acts as a deterrent to drinking further alcohol
  5. Initially, maximum 500 mg once daily for 1–2 weeks