May 23, 2013 · The combination atosiban + nifedipine exerts on additive tocolytic effect on the contractility of myometrial strips in both pre-term and term patients
Nifedipine had a higher success rate for inhibiting threatened preterm contractions
This topic last updated: Sep 05, 2023
Nifedipine is part of a group of medications called calcium channel blockers
It is recommended Donate Authors' conclusions: Calcium channel blockers (mainly nifedipine) for women in preterm labour have benefits over placebo or no treatment in terms of postponement of birth thus, theoretically, allowing time for administration of antenatal corticosteroids and transfer to higher level care
12 mg intramuscularly every 24 hours for 2 doses Dexamethasone (Decadron® ) Corticosteroid
See NICE's information on prescribing medicines
If you deliver before 34 weeks, receiving corticosteroid injections can improve your baby's chances of doing well
Nifedipine is a calcium channel blocker in the dihydropyridine subclass
United States National Library of Medicine
Pettibone DJ, Clineschmidt BV, Kishel MT, Lis EV, Reiss DR, Woyden CJ, et al
To establish a cause, if possible, of preterm labour, this may allow treatment of the primary cause of the preterm labour e
Calcium channel bloc: Nifedipine is a common calcium channel blocker that is used commonly as an antihypertensvie
Your doctor will probably decrease your dose gradually
Materials and methods: A randomized, double-blinded, placebo-controlled study with 206 threatened preterm labor patients was undertaken
You should not stop using nifedipine suddenly
Once uterine contractions stop and the woman is stabilized, she is usually switched to an oral agent and weaned from the magnesium sulfate
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Nifedipine can cause hypotension in a client who is hypovolemic
Do not stop taking this drug all of a sudden without calling your doctor
Uses: Preterm labor
4 It is not desirable to stop the delivery in the case of preterm labor
CSA
It's typically given as an injection under close medical supervision
08 days with nifedipine alone in the present study
This newborn's heart rate was 120/min, which is a score of 2
Administration of nifedipine failed in 5 cases including one case in which it was necessary to change the tocolytic and 4 cases in which delivery occurred less than 48 hours after the first dose of nifedipine
A neonatal intensive care unit (NICU) provides specialized care for preterm babies
Method: This was a randomized, double-blind, placebo-controlled trial of nifedipine in women with a singleton pregnancy between 28 0/7 and 33 6/7 weeks of gestation who were admitted with uterine activity, intact membranes, and cervical dilatation from 2 to 4 cm
6% need to stop treatment with the nifedipine and 8
It is also prescribed in the treatment of Raynaud's phenomenon, which is a condition caused by poor circulation to the hands and feet
There are several types, including: beta-adrenergic receptor agonists, calcium channel blockers, magnesium sulfate, and
Nearing 36 weeks now and will stop at 37 weeks
Women Nifedipine is recommended by ACOG and other experts as an appropriate drug of choice in pregnant women who require antihypertensive therapy
they originally used mag sulfate to stop my contractions
This drug should be used during pregnancy only if the benefit outweighs the risk to the fetus
Risk Summary: This drug has been shown to be teratogenic in animal models
5
Nifedipine should be stored at room temperature (68 to 77 degrees Fahrenheit)
Practice Essentials
First-line agents used to delay delivery up to 48 hours include calcium channel blockers (e
Nifedipine and other tocolytic drugs might stop preterm labor for two to seven days, providing time to use corticosteroids to help reduce complications in the fetus
Calcium channel blockers (mainly nifedipine) for women in preterm labour have benefits over placebo or no treatment in terms of postponement of birth thus, theoretically
Nifedipine is superior to β₂-adrenergic-receptor agonists and magnesium sulfate for tocolysis in women with preterm labor
Preterm birth can result in problems of the lungs, heart, brain, and other body systems of a newborn baby
Nifedipine (sold under the brand names Procardia, Adalat,) is a calcium ion influx inhibitor and is used as an antihypertensive medication, which helps in managing
Materials and methods: A randomized, double-blinded, placebo-controlled study with 206 threatened preterm labor patients was undertaken
If you need surgery, tell the surgeon ahead of time that you are using nifedipine
Once uterine contractions stop and the woman is stabilized, she is usually switched to an oral agent and weaned from the magnesium sulfate
[Adapted from NICE's full guideline on preterm
NYU Langone doctors advise drinking enough water to ensure your urine is pale yellow or almost clear—for most women, this is about 8 glasses (8 ounces each) per day
Nifedipine can cause hypotension in a client who is hypovolemic
Compare risks and benefits of common medications used for Premature Labor
If you need to stop this drug, you will want to slowly stop it as ordered by your doctor
(Indomethacin) NSAID (prostaglandin inhibitor) used to treat early (<30 wk) preterm labor or PTL associated with hydramnios; Should not be used for >48 hours because drug decreases rena blood flow and can promote oligohydramnios; Dosage of 100mg per rectum followed by 50mg PO every 6 hours for 8 doses; Can also A family or personal history of premature labor; Getting pregnant too soon after having a baby; Symptoms
2 The treatment for preterm labor includes bed rest and hydration
It will depend on how old your child is and PE with severe symptoms, usually IV formulation
5 cm and effacement less than 50%
Immediate-release doses above 120 mg/day are usually not needed
Do not suddenly stop taking nifedipine
Administration of nifedipine failed in 5 cases including one case in which it was necessary to change the tocolytic and 4 cases in which delivery occurred less than 48 hours after the first dose of nifedipine
A change in type of vaginal discharge—watery, bloody, or with mucus