Use only if clearly needed and benefit outweighs potential risk AU TGA pregnancy category: D US FDA pregnancy category: Not assigned Risk Summary: This drug can cause fetal harm when administered to pregnant women
This information is based on available
Topiramate and pregnancy Topiramate has been linked to a small, increased risk of problems for your baby if you take it during pregnancy
Topiramate is used off label in IIH supported by in vivo19 and open-label study evidence
Scientifically speaking, Topamax is classified as a Pregnancy Category D medication by the U
Drug FDA pregnancy category* AAP rating Lactation risk category†; Anxiolytics and hypnotics: Benzodiazepines: Alprazolam (Xanax) D: Unknown, of
20, 37 New data emerged from the North American Antiepileptic Drug Pregnancy Registry indicating an
You should seek advice from your doctor or pharmacist about taking this medicine
Twenty-two women taking topiramate during pregnancy and postpartum had measurements of topiramate in colostrum taken on day 3 or 4 postpartum for routine monitoring
The key antiepileptic drugs were selected for the review on the basis of their place in UK clinical practice
Over the last few years we have seen several studies suggesting an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy
Topamax increases the risk of major congenital malformations, including but not limited to cleft lip and/or cleft palate (oral clefts), which occur early in pregnancy before many women know they are pregnant
Use is contraindicated
The FDA warned that oral clefts develop during the first trimester of pregnancy, which is usually before women know they are
If you are not pregnant or planning to become pregnant, use effective birth control to prevent pregnancy while taking topiramate
Over the last few years we have seen several studies suggesting an increased risk of oral clefts in infants exposed to topiramate during the first trimester of pregnancy
Propranolol, topiramate, amitriptyline, fluoxetine, and gabapentin are pregnancy category C drugs
EMA’s safety committee ( PRAC) recommends new measures to avoid exposure of children to topiramate-containing medicines in the womb, because the medicine may increase the risk of neurodevelopmental problems after exposure during pregnancy
A FDA pregnancy category D drug, Topamax is not recommended during pregnancy
To assess the relative risk of oral clefts associated with maternal use of high and low doses of topiramate during the first trimester for epilepsy and nonepilepsy indications