Patients should be monitored closely for signs of digoxin toxicity; hypertension and reduced coronary flow (ref 1) Either dilute at least four fold (add 4ml to 1ml) with either Sodium chloride 0
Generic name: digoxin (oral/injection) [ di-JOX-in ] Brand names: Digitek, Digox, Lanoxin, Lanoxicaps, Cardoxin Drug classes: Group V antiarrhythmics, Inotropic
Class
Intravenous administration is preferable to intramuscular
Arrhythmia in children (consider toxicity) Other side effects of digoxin include: Visual disturbance (blurred or yellow vision) Heart block
Medicines A to Z Digoxin How and when to take digoxin Brand name: Lanoxin Dosage The first time you take digoxin you may be asked to take several tablets (or amounts of
If this is not possible, sample at least 6 hours or later after the last dose, regardless of the route of administration or the formulation used
3 Loading Dose 2
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Intramuscular
Irregular heartbeat
Lanoxin is supplied as 125-mcg (0
For example, digoxin is found to have 100% bioavailability in the micronized tablet
Intramuscular injection can lead to severe pain at the injection site, thus intravenous administration is preferred
En route to the labor and delivery Oral administration of flecainide or propafenone is feasible and safe and effectively converts recent-onset atrial fibrillation to sinus rhythm
The incomplete absorption is due to the effect of P-glycoprotein, an enterocyte efflux pump that ejects absorbed digoxin molecules back into gut lumen
The route of administration is the most important determinant of toxicity
Medications given via the IV route enter the bloodstream immediately, so extreme
(8) Serum digoxin concentrations should be obtained at least 6–8 hours after the last dose, regardless of the route of administra- If this is not possible, sample at least 6 hours or later after the last dose, regardless of the route of administration or the formulation used
(especially if administered rapidly via IV route) may produce serious arrhythmias in digitalised The route of medication administration can change dependent on client factors
Inadvertent digoxin administration into the intrathecal space was suspected, and a digoxin level was ordered and detected
Do not stop taking this medicine without first checking with your doctor