Sep 3, 2005 · Gabapentin is a GABA analogue used in the treatment of epilepsy, neurogenic pain, restless-leg syndrome, essential tremor, bipolar disorder, and migraine prophylaxis; it was first reported for its effects on hot flashes in five women and one man
02, NNT = 6) Somnolence; dizziness: Ginseng 48: 384 menopausal women: 200 mg per day: Four months: Gabapentin is an anti-seizure medication that's moderately effective in reducing hot flashes
Print Diagnosis Signs and symptoms of menopause are usually enough to tell most women that they've started the menopausal transition
At doses used to control hot flashes, gabapentin was well tolerated, with drowsiness as its most reported adverse effect
, MD Authors Info & Affiliations June 13, 2000 issue 54 ( 11) 2161-2163
Gabapentin 300 mg/day could be useful to relieve hot flashes in women for whom hormone therapy is not suitable or when hot flashes do not respond to other therapies
Starting in 2000, a
In other studies, it appears that gabapentin may improve sleep in people with other medical conditions that make it more difficult to sleep, such as alcohol
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[ 1, 2] However, these are often ignored due in part to their relatively benign nature
While triggers of hormone decreases differ for men and women Data presented at the annual meeting of the American Society of Clinical Oncology indicate that pregabalin (Lyrica), an anticonvulsant drug similar to gabapentin, may also be helpful for alleviating hot flashes
The prevalence, pathophysiology, and treatment of hot flashes will be reviewed here
A 2005 study by Pandya et al
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and the seizure drug, gabapentin
5 mg) estrogen-only HRT (97 women) 75 mg Effexor (96 women) placebo (sugar pill) (146 women) After 8 weeks, the number of hot flashes per day most women were having dropped from eight to four -- a 50% decrease
Additionally, the results corroborate that gabapentin effectively decreases hot flashes for eight weeks beyond the initial four weeks, which were tested in the randomized portion of this protocol
Article abstract The author describes six cases in which gabapentin treatment reduced the frequency of hot flashes
0 per day Patients typically receive a lower dose for hot flashes than for treating depression
Antiseizure medications, such as gabapentin (Neurontin®) Oxybutynin (Oxytrol®, Ditropan XL®) which is also used to
Phase 3 randomized controlled study of gastroretentive gabapentin for the treatment of moderate-to-severe hot flashes in menopause