Feb 17, 2020 · Mechanism of Action
Isosorbide mononitrate is a nitrate that dilates(widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump
Take the first dose in the morning right after you wake up, and the second dose 7 hours later
bladder pain
Isosorbide mononitrate tablets, USP, for oral administration, contain 10 mg or 20 mg of isosorbide mononitrate (diluted), USP
Isosorbide mononitrate (ISMN), an organic nitrate and the major biologically active metabolite of isosorbide dinitrate (ISDN), is a vasodilator with effects on both
25–50 mg once daily, then increased if necessary to 50–100 mg once daily, dose to be taken in the morning, the lowest effective dose should be used
Drug
Isosorbide Mononitrate Extended-Release Tablets
Of the total drug interactions, 19 are major, 188 are moderate, and 2 are minor
Each tablet, for oral administration, contains either 30 mg, 60 mg or 120 mg of isosorbide mononitrate in an extended-release formulation
50, 56, 60, 100 or 500 tablets
Take the first dose in the morning right after you wake up, and Imdur is an extended release tablet used to prevent angina attacks (chest pain)
Each tablet, for oral administration, contains either 30 mg, 60 mg or 120 mg of isosorbide mononitrate in an extended-release formulation
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A single dose of 20 mg of isosorbide dinitrate was administered to healthy subjects after pretreatment with 80 mg propranolol three times daily for 48 hours, resulting in no impact on the pharmacokinetics of isosorbide dinitrate and isosorbide-5-mononitrate
The older group (65 to 74 years) showed 30% lower apparent oral clearance (Cl/F) following the higher dose, i
The administration of isosorbide mononitrate extended-release 120 mg (2 x 60 mg tablets every 24 hours for 7 days) produced a dose-proportional increase in C max and AUC, without changes in T max or the terminal half-life
Tablets may be taken with or without food, and should be swallowed whole and not chewed
2 x 60mg tablets taken in the
It works by Isosorbide mononitrate, sold under many brand names, is a medication used for heart-related chest pain ( angina ), heart failure and esophageal spasms
The company recommends not splitting the 30 mg tablets despite Long-Term Care Advise ERR April 2017 Volume 5 Issue 4 Page 2 >Crushing or splitting —continued
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You should consult your health care professional before taking any drug, changing your diet, or commencing or discontinuing any course of treatment