Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis
Lioresal intrathekal darf nur intrathekal (in den Rückenmarkskanal) verabreicht werden
Its chemical name is 4-amino-3-(4-chlorophenyl) butanoic acid, and its structural formula is:
Intrathecal baclofen therapy (ITB therapy) is delivered by the Medtronic SynchroMed ® II Drug Infusion System, which consists of an implantable, programmable pump and an intrathecal catheter
Lioresal Intrathecal belongs to a group of medicines called muscle relaxants
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Lioresal intrathekal darf nur intrathekal (in den Rückenmarkskanal) verabreicht werden
Careful monitoring of respiratory and cardiovascular functions is Warning
LIORESAL INTRATHECAL when introduced directly into the intrathecal space permits effective CSF concentrations to be achieved with resultant plasma concentrations 100 times less than those occurring with oral administration
A doctor will surgically place the pump and monitor the dose of the medication Lioresal® Intrathecal (baclofen injection) Indications and Usage Lioresal® Intrathecal is intended for use by the intrathecal route in single bolus test doses (via spinal catheter or lumbar puncture) and, for chronic use, only in implantable pumps approved by the FDA specifically for the administration of Lioresal® Intrathecal into the In addition, hypotension has been reported with concomitant use of morphine and intrathecal baclofen
5 The pump has an alarm that will sound when the reservoir of Lioresal ® is
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Treatment should be started with a dosage of 15 mg daily, preferably in divided doses
Google Scholar; and can be assumed not to be irritating as it is administered intrathecally, we decided to apply the intrathecal formulation subcutaneously and gradually reduce the dose
did not affect coordination in mice
Lioresal Intrathecal 50 micrograms/1ml is intended for administration in single bolus test doses (via spinal catheter or lumbar puncture) and, for chronic use, in implantable pumps suitable for continuous administration of Lioresal Intrathecal 10mg/20ml and 10mg/5ml into the intrathecal space (EU certified pumps)
Dieses Arzneimittel ist in den Mitgliedsstaaten des Europäischen Wirtschaftsraumes (EWR) unter den folgenden Bezeichnungen zugelassen: Deutschland: Lioresal Intrathecal 10 mg/ 5 ml Infusionslösung
Lioresal ® Intrathecal (baclofen injection) is a muscle relaxant and antispastic that is indicated for use in the management of severe spasticity of cerebral or spinal origin