For that reason, the veterinarian will need to monitor the digoxin blood levels throughout Toxicokinetics
DIGIFab is indicated for the treatment of patients with life-threatening or potentially life-threatening digoxin toxicity or overdose, including: Known suicidal or accidental
Introduction Digoxin is a cardiac glycoside derived from Digitalis lanata ( Hollman, 1996 )
Learn more from epocrates about Digoxin overdose, including symptoms, causes, differential diagnosis
Precipitating factors for
Laboratory investigations revealed a serum digoxin concentration (SDC) of 7
Uses for Digoxin Heart
5 mg
Digoxin overdose Also known as: Cardiac glycoside toxicity, digoxin toxicity, digoxin poisoning 1
Toxicity from digoxin poisoning usually manifests within 6 h of the last dose, whether this follows acute or chronic poisoning
Immunoglobulin Fab Fragments
This article outlines the indications, action, and contraindications for digoxin as a valuable agent in managing heart failure and certain arrhythmias
The fatal dose for humans is about 10 to 20 mg per kg of bodyweight, which means that a person who weighs 100 pounds would need to consume 1,000 to 2,000 milligrams (mg) of foxglove leaves before they could experience toxicity symptoms
Patients with acute cocaine toxicity presenting to the emergency department (ED) may require urgent treatment for tachycardia, dysrhythmia, hypertension, and coronary vasospasm, leading to pathological sequelae such as acute coronary syndrome, stroke, and death
In these studies
) in man, whereas the lethal unit of gitalin in animals is observed to be at least five times that of Digoxin
Digoxin toxicity is related to serum concentration
The ED50 is the dose of a medication that produces a specific effect in 50% of the population that has been administered that dose
Valproate toxicity may occur when increasing the dose of the medication to achieve the desired therapeutic effect
On the other hand, the mean lethal dose of digoxin was 8
For the majority of patients with clonidine toxicity, the prognosis is good with treatment
Salicylate levels greater than 100 mg/dL are considered severe toxicity and occur 12 to 24 hours after ingestion
26 adult rats and 23 adult guinea-pigs were anaesthetized with pentobarbitone and injected subcutaneously with varying doses of digoxin
This patient’s toxicity management included digoxin antibody fragment