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Overview Test Id : LAMO Order This Test Lamotrigine, Serum Useful For Monitoring serum concentration of lamotrigine Assessing compliance Adjusting lamotrigine
Highlights About Side effects Interactions Other warnings Dosage Take as directed Important considerations Alternatives Drug Images This drug
Canadian Brand Name lamoTRIgine lamoTRIgine-100 lamoTRIgine-150 lamoTRIgine-25 Mylan-lamoTRIgine Teva-lamoTRIgine Descriptions
However, if ineffectiveness, poor adherence or toxicity is suspected blood plasma
sores, ulcers, or white
However, the dose is usually not more than 250 mg a day
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23 Routine blood monitoring of lamotrigine is not recommended
Lamotrigine plasma level can be significantly influenced by inducers or inhibitors : Centrifuge and separate blood as soon as possible after collection
and the lamotrigine levels double (1, 2)
Carbamazepine and estradiol induce UGT1A4, which lowers lamotrigine levels
Most of these symptoms are dose related, and may Initial dose: 0
Given the reported association between lamotrigine and hemophagocytic lymphohistiocytosis (HLH) since at least 2007 and a recent US Food and Drug Administration warning about this serious adverse effect of lamotrigine, HLH was suspected
Aplastic anaemia, bone-marrow depression, and pancytopenia have been associated rarely with lamotrigine
Detecting drug levels in the blood help in proper seizure control and reduction of side effects of the drug
Blood: Container/Tube
Lamictal is a prescription drug used to treat bipolar disorder and epilepsy
Your lamotrigine level should be drawn 12 hours after your nighttime dose
As mood-stabilizer and anticonvulsant drug, lamotrigine has a TDM level of recommendation of 2 (Recommended)
Plasma levels of Lamotrigine correlate poorly with clinical effectiveness, so analysis is usually unhelpful
[1][2][3][4] Introduction: Lamotrigine is widely used for mood disorders including bipolar disorder and major depression, but its therapeutic levels have yet to be determined