Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand
Dec 30, 2022 · The way clopidogrel works is thought to be due to its active thiol metabolite, which inhibits the binding of adenosine diphosphate (ADP) to its platelet receptor which indirectly inhibits platelet aggregation
Early Communication about an Ongoing Safety Review of clopidogrel bisulfate (marketed as Plavix)
In patients with ACS without ST segment elevation (NSTEMI), clopidogrel plus aspirin is able to reduce the relative risk of adverse cardiovascular events by 20%, compared with aspirin alone
Other options to manage these patients or scenarios include desensitization and switching to an alternative agent with a different structure (e
Do not use more than
The combination of clopidogrel and aspirin is better than aspirin or clopidogrel alone in preventing another heart attack but the risk of bleeding is higher
Compare Drugs Print Comparing Aspirin vs Clopidogrel Aspirin Clopidogrel Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood
painful or difficult urination
- 3,871 Clopidogrel bisulfate side effects and drug interactions
Clopidogrel may not work as well if you have certain genetic factors that affect the breakdown of this medicine in your body
Cardiovascular disease is the most common cause of death throughout the world
2 To address the issues of ease of administration and dosing Plavix is available commercially as either pink, round, biconvex, debossed, film-coated tablets containing 97
Since it's a blood thinner, possible side effects include bleeding and bruising, especially if you take medications that interact with clopidogrel (Plavix) like certain antidepressants, anticoagulants, or non-steroidal anti-inflammatory drugs (NSAIDs)
3, 5
Alternative treatments should be used for
The clinically important adverse reactions observed in trials comparing clopidogrel bisulfate Clopidogrel bisulfate at recommended doses forms less of the active metabolite and so has a reduced effect on platelet activity in individuals who are homozygous for no-function alleles of the CYP2C19 gene, (termed "CYP2C19 poor metabolizers")
For patients with non–ST-segment elevation ACS (unstable angina [UA]/non–ST-elevation myocardial infarction [NSTEMI]), Plavix has been shown to reduce the rate of myocardial infarction (MI) and stroke
It has a specific optical rotation of about +56°
It’s also available as brand-name Plavix, but the cash price of the brand-name drug is almost the same as the generic version