Minocycline is a second-generation, semi-synthetic tetracycline that is used as a broad-spectrum antibiotic against a wide range of microorganisms
2000
Minocycline pharmacokinetic study
Minocycline is a semisynthetic tetracycline that alleviates the degree of neuropathology in animal models of several neurological disorders, including stroke, 1,2 spinal cord injury, 3,4 multiple sclerosis, 5,6 and Parkinson's disease
Boosted by this success, the Calgary MS team is now eager to solidify the case for starting minocycline in patients with CIS as well as using it in RRMS patients
It seems that most published research on Antibiotics for MS has been done with Minocycline, I've only found one reference to a trial with Doxycycline
Minocycline is twice as strong as doxycycline but nonetheless very effective for MS
doi: 10
We have previously reported that minocycline decreased gadolinium-enhancing activity over six months in a small trial of patients with active relapsing-remitting MS (RRMS)
Expert opinion: Minocycline offers several distinct advantages in terms of well-known safety profile, lower cost of therapy, widespread availability, and being available as an oral formulation