It is intended for use in conjunction with a healthcare provider-supervised reduced-calorie diet
After four years, the cumulative incidence of diabetes was lower in the orlistat group (6
Studies have shown that, on average, orlistat, plus a weight-reducing diet and exercise, causes more weight loss than a weight-reducing diet and exercise alone
Last revised in August 2023 Contraindications and cautions Adverse effects Drug interactions What are the contraindications and cautions for orlistat? Do not prescribe
Weight reduction typically begins within 2 weeks of initiating orlistat
OTC (Alli): Up to 60 mg PO q8hr
Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or without fever; wheezing; tightness in the chest or throat;
If you occasionally miss a meal
Orlistat (Xenical®) was first approved by the FDA in 1999
, Xenical) is used as an adjunct to caloric restriction, increased physical activity, and behavioral modification in the treatment of exogenous obesity; also used to reduce the risk of weight regain after initial loss
Those who received orlistat 30 mg had an average regain of 53
The study duration was 5 years, and the mean duration of treatment with sibutramine was about 3
8 months, and this was slightly longer for women than for men
It is also used in overweight people who may also have diabetes, high blood pressure, high cholesterol, or heart disease
May omit dose if a meal is occasionally missed or contains no fat
Davis PT Collection
Orlistat when taken with meals inhibits the digestion of dietary fats and prevents their absorption, thus reducing caloric intake
4kg, whereas sibutramine recipients lost 8
9%) decreased the dose or discontinued at least one oral diabetes medication during the study; conversely, dose increase or the addition of at least one new diabetes medication occurred less frequently in orlistat- (14
Therefore, when you use orlistat you should take a daily multivitamin that contains vitamins A, D, E, K, and beta-carotene
Side effects of orlistat
How This Medicine Works: Orlistat is in a class of medications called lipase inhibitors
Take Orlistat at the same time every day for the ease of remembering
If you take more Orlistat than you should If you take more capsules than you have been told to take, or if someone else accidentally takes your medicine, contact a doctor, pharmacist or hospital as you may need medical attention