Angioedema is a rare side effect associated with the use of losartan
1999 Sep;33 (9):936-8
To report a case of angioedema associated with the angiotensin II receptor antagonist losartan
Although angioedema due to ACEI is a well-known side effect, only a few cases are associated with ARBs, such as losartan
Angioedema may co-exist with urticaria, which is typically an itchy,raised, red rash with indistinct margins
As a result, losartan relaxes the blood vessels
Current practice and guidelines Authors in the recent past have recommended that physicians not prescribe ARBs to patients who have had an episode of angioedema with ACEIs because it can be life-threatening ( 15 , 24 )
This paper will discuss a case of angioedema induced by losartan, an ARB; there have been only twenty case reports published to our knowledge documenting losartan-induced angioedema
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Medication-induced angioedema has been known for many years; however, the mechanism by which many medications cause angioedema is not clearly understood
Angioedema is most commonly histamine-mediated; mast cell and basophil stimulation results in histamine release
Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world
Angioedema is defined as the localized swelling of subcutaneous and submucosal tissue caused by the extravasation of fluids into the interstitial space [1]
Sometimes the bowel may also become swollen, which can cause stomach pain
Swelling of the tongue or throat requires immediate emergency medical treatment
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Angioedema (an allergic reaction) with other blood pressure medicines (eg, benazepril, enalapril, lisinopril, Lotrel®, Vasotec®, Zestoretic®, Zestril®), history of—Use may cause this condition to reoccur
Angioedema is the swelling of mucosa and submucosal tissue